What are the classic symptoms of Plummer-Vinson Syndrome?

The classic symptoms of Plummer-Vinson Syndrome include a triad of esophageal webs, glossitis, and iron deficiency anemia. The presence of esophageal webs is significant as they contribute to swallowing difficulties (dysphagia) due to the narrowing of the esophagus. Glossitis, which is characterized by inflammation of the tongue, often manifests as a smooth, red tongue and can be linked to nutritional deficiencies. Iron deficiency anemia is a critical component of this syndrome, frequently resulting from the combination of chronic iron deficiency and malabsorption due to the structural changes in the esophagus.

This combination of symptoms is distinctive for Plummer-Vinson Syndrome, differentiating it from other conditions. Other options may mention symptoms that could be seen in other gastrointestinal disorders or nutritional deficiencies, but they do not capture the specific triad characteristic of Plummer-Vinson Syndrome.