What type of bacteria are Tetracyclines primarily used against?

Tetracyclines are broad-spectrum antibiotics effective against a wide range of bacteria, including both Gram-positive and Gram-negative organisms. Their mechanism of action involves inhibiting protein synthesis by binding to the 30S ribosomal subunit, which is a process that occurs in many types of bacteria. This broad efficacy makes them useful in treating various infections caused by diverse bacterial pathogens.

In addition to their activity against common Gram-positive bacteria, such as Staphylococcus and Streptococcus species, Tetracyclines also show effectiveness against many Gram-negative bacteria. This includes organisms like Escherichia coli and certain strains of Neisseria. Their ability to penetrate bacterial cells allows them to address infections from a variety of sources, which is why they are often considered a versatile option in the treatment of infectious diseases.

Other choices, such as focusing solely on Gram-positive or Gram-negative bacteria, would overlook this broad-spectrum capability. Additionally, fungi, as a different class of pathogens, are not susceptible to Tetracyclines, which clarifies why the answer does not include that option.